Women with BRCA1 mutations should remove their ovaries by age 35, according to a study that published online Monday.

People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of them doesn't function. For cancer-suppressor genes like BRCA1 ...

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

The research, published in Nature Communications, suggests this preemptive, two-part approach could be the most effective plan of treatment for early-stage breast cancer linked to BRCA1 and BRCA2 ...

The tumour suppressor breast and ovarian cancer type 1 susceptibility protein (BRCA1) is integral for the maintenance of genome stability through its roles in cell cycle checkpoint control and DNA ...

The tumour suppressor BRCA1 is mutated in familial breast and ovarian cancer. Now, Shuklaet al.demonstrate that mice lacking BRCA1 in cardiomyocytes are more sensitive to ischaemia than control ...

A method for detecting a germline alteration in a BRCA1 gene, said alteration selected from the group consisting of the alterations set forth in Tables 11 and 12 which comprises analyzing a ...

Doctors have long recognized that women with mutations in two particular genes – BRCA1 and BRCA2 – have a higher risk of breast and ovarian cancer.

BRCA1 is one of the best-studied cancer genes in the world. Still, on occasion, doctors will test a patient and find a BRCA1 mutation no one has ever seen before. This creates a dilemma. The newly ...

The full name of the BRCA1 gene is “breast cancer 1, early onset” and it codes for a tumor suppressor protein. This article explores the gene function of the BRCA1 gene.

Learn what the BRCA gene does and how mutations in this gene may affect your chances of developing prostate cancer.

People who carry a BRCA gene mutation are at elevated risk for breast cancer, ovarian cancer, cervical cancer, uterine cancer, pancreatic cancer, stomach cancer, melanoma, and gallbladder cancer.