The simplest one is to wager on the in-form golfers, a list led by Rory McIlroy and Scottie Scheffler. McIlroy may get the nod over Scheffler in some circles this week because he's playing on home soil at Royal Portrush in Northern Ireland.

The 153rd Open Championship, also referred to as the British Open, will tee off Thursday, July 17 with the competition returning to the Royal Portrush Golf Club after previously being hosted there in 2019.

Brooks Koepka enters play in the 2025 Open Championship at Royal Portrush Golf Club with +5500 odds to win. In his last event at this course he finished fourth in the 2019 The Open Championship. In his four tournaments during the past year, Koepka has a best finish of 12th and an average finish of 28th, with two made cuts.

But nobody should ever mistake artificial intelligence for being sappy. USA TODAY Sports canvassed five major AI programs seeking their predictions for the 2025 Open Championship winner and top sleeper picks. The majority went with the pre-tournament favorite, Scottie Scheffler, who is seeking his first Claret Jug.

SportsLine golf expert Eric Cohen locked in a $10 eight-leg PGA Tour parlay that would return nearly $1.1 million for the British Open 2025

M Open odds have dropped, and U.S. Ryder Cup hopefuls are among the top betting favorites. Here's what you need to know.

Robert MacIntyre, who placed sixth in the 2019 The Open Championship at Royal Portrush Golf Club, comes into the 2025 Open Championship with +3500 odds to win as he tries for another strong performance. In the past 12 months, MacIntyre has played in 23 tournaments. His best finish was second, and his average finish was 27th, with one top five.

The World No. 1 and tournament favorite shot a 7-under par 64 in the second round at Royal Portrush Golf Club in Northern Ireland as he zoomed to the top of the leaderboard. Scheffler sits at -10 entering the third round on Saturday, July 19, one stroke better than Matt Fitzpatrick, who is -9 through two rounds.