A who’s-who squad of MLS’ biggest names will take on their counterparts from Liga MX in the MLS All-Star Game on Wednesday, set to take place for the first time at Austin’s Q2 Stadium.

Lionel Messi and Sergio Ramos, once fierce rivals in Spain and later teammates in Paris, will reunite this week as opponents in the 2025 MLS All-Star Game in Austin, Texas. Messi was with Barcelona and Ramos with Real Madrid in El Clásico.

Lionel Messi was one of 12 players voted onto the roster by MLS fans for the 2025 MLS All-Star Game in Austin.

It isn’t shocking to see Lionel Messi all over 2025 Topps Now MLS’s checklist. He’s been the MLS Player of the Matchday a league-leading four times in 2025 and his 23 goal-contributions in MLS is good for a tie for the second-most in the league entering Matchday 26.

Argentine GOAT moved to America in 2023Yet to trigger extension option in his contractIs being linked with teams around the worldFollow GOAL on WhatsApp! 🟢📱WHAT HAPPENED?As things stand, eight-time Ballon d’Or winner Messi is only under contract in South Florida until the end of the calendar year.

Messi could be heading into one of the most intense stretches of his career. During the MLS season, Inter Miami also played four matches in the Club World Cup. After their run ended in the Round of 16, they were back in MLS action just a week later. And soon, the League Cup kicks off.

MLS season rolled on with another busy week in the middle of the summer with several teams taking on two games this week.

For Major League Soccer's 30th season, USA TODAY Sports picks the 30 best players in MLS history. Did your favorites make the list?