President Donald Trump’s ambitious agenda may be on the brink of a stinging setback in the House before it even gets started, offering a flashing warning sign about Speaker Mike Johnson’s ability to deliver other key White House priorities this year.

President Donald Trump jumped in Tuesday to help House Speaker Mike Johnson try to muscle a GOP budget blueprint to passage, a step toward delivering his “big, beautiful bill” with $4.5 trillion in tax breaks and $2 trillion in spending cuts over stiff opposition from Democrats — and even some Republicans.

House Republicans on Tuesday advanced a framework for President Trump’s “big, beautiful” agenda package on taxes, border security, energy supply and more, teeing up a final floor vote on the measure as soon as Tuesday evening.