Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia. How this happens remains largely ...

New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications ...

New research from Colorado State University into the ways neurons regulate chemical balance in the brain could provide valuable insights toward developing therapies for disorders such as epilepsy.

An interdisciplinary team of scientists at the Max Planck Florida Institute for Neuroscience have developed a novel approach to measure the activity and strength of individual synapses that drive a ...

The death of synapses, and the neurons that need them, marks the inevitable endgame of Alzheimer’s disease. Despite this eventual synaptic mayhem, a new work, led by Thomas Südhof and Marius Wernig at ...

Whether picking up a small object like a pen or coordinating different body parts, the cerebellum in the brain performs essential functions for controlling our movement. Researchers investigated how a ...

Clinical portfolio, informed by deep and novel synapse biology and pharmacology insights, aims to strengthen neural connections through event-driven pharmacology Lead candidate zelquistinel is ...

Psychedelics stimulate the growth of synapses outside the brain, scientists show for the first time. Many psychedelics act by binding to serotonin receptor 2. Manor and his team found that these ...