Seattle Seahawks, Tory Horton
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The 49ers surged to the NFC's top seed in 2023 when they finished 12-5 and won the NFC West division. Including that year, each of the previous two times the Niners had the No. 1 seed under Shanahan they've advanced to the Super Bowl. -- Wagoner
The Rams are resting starters after clinching the NFC West last weekend and the Seahawks lead the Week 18 matchup between NFC West rivals 17-13 at halftime.
National Football League odds courtesy of BetMGM. Odds updated Friday at 9:34 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub. Spread favorite: Seahawks (-2.