The Bills are road favorites against the Jaguars in the wild-card round of the NFL playoffs. As the wild-card round unfolds, you'll notice that the bracket is wide open for a team to exert their dominance or pull off an upset. One of the best end-zone threats in the NFL is expected to return to the Rams for the postseason.

Wild Card Weekend will kick off in North Carolina and end in Pittsburgh. The NFL on Sunday night announced the schedule for the opening round of the playoffs, which begins with the NFC's fourth-seeded Carolina Panthers hosting the No. 5 Los Angeles Rams on Saturday at 4:30 p.m. ET on FOX.

Wild-card weekend wraps up with a battle between the Texans and the Steelers clinched the AFC North with a win over the Ravens on Sunday. Their wild-card round matchup kicks off at 8:00 p.m. on Monday and will be aired on ESPN and ABC.

As announced on Sunday night, the Panthers will host the Los Angeles Rams for their wild-card weekend matchup at 4:30 p.m. ET on Saturday, Jan. 10. The game will be broadcast by FOX.

The NFL released the wild-card weekend schedule for the opening round of the playoffs. Here are the winners and losers of the scheduling spots.

Denver will get the first-round bye while New England and Jacksonville play on Wild Card Weekend — and neither has an easy matchup. Chargers vs. Patriots will feature two of the NFL’s best young quarterbacks with Drake Maye and Justin Herbert facing off. The Jaguars drew the shortest straw and will have to host Josh Allen.

Must-win AFC North and NFC South showdowns? No. 1 seeds on the line? We have picks, predictions, stats and what's at stake for every Week 18 game.

The Bills had the best rushing attack in the NFL this year with an average of 159.6 yards per game. Only one other team in the NFL even topped145 yards per game during the regular season. The Bills went 9-0 in games where they rushed for at least 150 yards thanks in large part to their not-so-secret weapon, James Cook.

What you should knowThe Eagles (11-6) will face the San Francisco 49ers (12-5) Sunday at 4:30 p.m. on Fox in the wild-card round of the playoffs. Here's the full wild-card schedule. Nick Sirianni defended his decision to rest his starters with the No.