Cyclophosphamide is widely used to treat severe manifestations of numerous autoimmune rheumatic diseases including systemic sclerosis. Based on recent data, immunological and inflammatory activation ...

Patients who underwent autologous stem cell transplantation (ASCT) for diffuse cutaneous systemic sclerosis (dcSSc), also known as scleroderma, did no better than others receiving conventional ...

An anti-cancer drug that suppresses the immune system is the first drug that has been shown to alleviate the most devastating effects of scleroderma, a disease of the connective tissues and lungs.

Please provide your email address to receive an email when new articles are posted on . CHICAGO — A long-term follow-up to the Scleroderma: Cyclophosphamide or Transplantation trial demonstrated that ...

New clinical trial findings show that a therapeutic regimen involving transplantation of a person's own blood-forming stem cells can improve survival and quality of life for people with severe ...

SAN DIEGO-A drug that suppresses the immune system and reduces inflammation has been shown to be effective in treating lung disease associated with the devastating connective tissue disease ...

The approach could represent the first new treatment to improve survival in patients with severe scleroderma in more than four decades. An unusual autoimmune disease that causes skin and lung damage ...

Please provide your email address to receive an email when new articles are posted on . The last 3 years of drug development in scleroderma have come to represent everything that ails the current ...

Scleroderma with internal organ involvement is a debilitating and lethal autoimmune disorder with few effective treatments. But a study has now found new cause for optimism using an aggressive stem ...

First Bari Martz’s fingers turned blue. Then she started gasping for breath, and her joints stiffened so that she couldn’t even open her hands. Subscribe to read this story ad-free Get unlimited ...

Alicia M. Hinze, MD: In regard to treatment options, I’ll speak from the rheumatic side of treating interstitial lung disease, using scleroderma as probably 1 of the prototypical rheumatic diseases in ...

Cyclophosphamide is well established as a potential treatment for severe manifestations of SSc. Recent data point towards limited efficacy in SSc-ILD with positive outcomes in lung function, ...