The Houston Texans plan on playing starters today against the Indianapolis Colts, though one key offensive weapon won't suit up for the season finale.

The Texans and Colts will kickoff in NRG Stadium at 12 p.m. CT, likely with Collins supporting on the sidelines, as Houston will look to put together a ninth win in a row, and potentially claim a third-straight AFC South title, if able to get some extra help from the Tennessee Titans against the Jacksonville Jaguars.

The Texans face the Colts in Houston on Sunday. We break down what the game means for the NFL playoff picture in Week 18.

The Indianapolis Colts visit the Houston Texans in NFL Week 18: Inactives, injury report, who's in, who's out.

Riley Leonard is set to get his first start at quarterback with the hopes to, not only establish himself as Indy's QB2 going forward, but pull off a massive victory to help the Colts finish with a winning record, albeit 9-8.

According to the Texans ' inactive list, right tackle Trent Brown will miss Sunday's contest at NRG Stadium after dealing with a knee injury. This will be the second straight game he's missed after suffering a leg contusion in Week 16's win over the Las Vegas Raiders.

The Indianapolis Colts are listing six players as inactive in Week 18 against the Texans, including Phillip Rivers.

A few notable names out of the fold for the Colts, as well, the biggest difference-maker being Sauce Gardner, who's season has been brought to an end due to a calf injury, and will leave this Indianapolis secondary a bit shorthanded against a Texans receiving corps that won't include Nico Collins.

For Houston to win the division, they need to beat Indy, then also get help from Tennessee defeating Jacksonville. The winner of the AFC South would get the No. 3 seed (or higher), while the second-place finisher in the division would host as a wild card.