Jerry Tonelli talks to Mark Farrell outside Central Drug Store on Mission Street in the Excelsior. October 24, 2024. Photo by Kelly Waldron. “I think his campaign is fading fast. Most of the polling ...

Central Drug Store, a community staple in San Francisco's Excelsior District since 1908, will permanently shut down at the end of the day on July 15, 2025.

Family-owned Central Drug Store in San Francisco closes its doors after serving the community since the early 1900s, with owner Jerry Tonelli retiring after 50 years.